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Ultimate Human Podcast  ·  165 min

Mitochondria, Cold Exposure, and Cellular Resilience

Dr. Josh Axe on how cold exposure activates mitochondrial biogenesis, peptide therapy, and the cellular mechanisms behind hormetic stress adaptation.

Key Insights

Cold exposure triggers mitochondrial biogenesis through controlled cellular stress

Peptide therapy can enhance recovery and metabolic function when combined with environmental stressors

Parasite infections impair mitochondrial function—addressing gut health amplifies cold therapy benefits

Hormesis operates at the cellular level: stress signals activate protective pathways

"The body adapts to what you consistently demand of it—controlled stress builds resilience when applied deliberately."
— Ultimate Human Podcast
cold exposure recovery hormesis